Mechanisms of Assembly and Cellular Interactions for the Bacterial Genotoxin CDT

Many bacterial pathogens that cause different illnesses employ the cytolethal distending toxin (CDT) to induce host cell DNA damage, leading to cell cycle arrest or apoptosis. CDT is a tripartite holotoxin that consists of a DNase I family nuclease (CdtB) bound to two ricin-like lectin domains (CdtA...

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Detalles Bibliográficos
Autores principales: Nesic, Dragana, Stebbins, C. Erec
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287909/
https://www.ncbi.nlm.nih.gov/pubmed/16304609
http://dx.doi.org/10.1371/journal.ppat.0010028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287909/
https://www.ncbi.nlm.nih.gov/pubmed/16304609
http://dx.doi.org/10.1371/journal.ppat.0010028

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