Cargando…
Mechanisms of Assembly and Cellular Interactions for the Bacterial Genotoxin CDT
Many bacterial pathogens that cause different illnesses employ the cytolethal distending toxin (CDT) to induce host cell DNA damage, leading to cell cycle arrest or apoptosis. CDT is a tripartite holotoxin that consists of a DNase I family nuclease (CdtB) bound to two ricin-like lectin domains (CdtA...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2005
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287909/ https://www.ncbi.nlm.nih.gov/pubmed/16304609 http://dx.doi.org/10.1371/journal.ppat.0010028 |