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Combinatorial diversity of fission yeast SCF ubiquitin ligases by homo- and heterooligomeric assemblies of the F-box proteins Pop1p and Pop2p

BACKGROUND: SCF ubiquitin ligases share the core subunits cullin 1, SKP1, and HRT1/RBX1/ROC1, which associate with different F-box proteins. F-box proteins bind substrates following their phosphorylation upon stimulation of various signaling pathways. Ubiquitin-mediated destruction of the fission ye...

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Detalles Bibliográficos
Autores principales: Seibert, Volker, Prohl, Corinna, Schoultz, Ida, Rhee, Edward, Lopez, Rebecca, Abderazzaq, Kareem, Zhou, Chunshui, Wolf, Dieter A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC128837/
https://www.ncbi.nlm.nih.gov/pubmed/12167173
http://dx.doi.org/10.1186/1471-2091-3-22