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StpA protein from Escherichia coli condenses supercoiled DNA in preference to linear DNA and protects it from digestion by DNase I and EcoKI

The nucleoid-associated protein, StpA, of Escherichia coli binds non-specifically to double-stranded DNA (dsDNA) and apparently forms bridges between adjacent segments of the DNA. Such a coating of protein on the DNA would be expected to hinder the action of nucleases. We demonstrate that StpA bindi...

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Detalles Bibliográficos
Autores principales: Keatch, S. A., Leonard, P. G., Ladbury, J. E., Dryden, D. T. F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289078/
https://www.ncbi.nlm.nih.gov/pubmed/16299353
http://dx.doi.org/10.1093/nar/gki951