CFTR Gating II: Effects of Nucleotide Binding on the Stability of Open States

Previously, we demonstrated that ADP inhibits cystic fibrosis transmembrane conductance regulator (CFTR) opening by competing with ATP for a binding site presumably in the COOH-terminal nucleotide binding domain (NBD2). We also found that the open time of the channel is shortened in the presence of...

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Detalles Bibliográficos
Autores principales: Bompadre, Silvia G., Cho, Jeong Han, Wang, Xiaohui, Zou, Xiaoqin, Sohma, Yoshiro, Li, Min, Hwang, Tzyh-Chang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289160/
https://www.ncbi.nlm.nih.gov/pubmed/15767296
http://dx.doi.org/10.1085/jgp.200409228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289160/
https://www.ncbi.nlm.nih.gov/pubmed/15767296
http://dx.doi.org/10.1085/jgp.200409228

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