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CFTR Gating II: Effects of Nucleotide Binding on the Stability of Open States

Previously, we demonstrated that ADP inhibits cystic fibrosis transmembrane conductance regulator (CFTR) opening by competing with ATP for a binding site presumably in the COOH-terminal nucleotide binding domain (NBD2). We also found that the open time of the channel is shortened in the presence of...

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Detalles Bibliográficos
Autores principales:	Bompadre, Silvia G., Cho, Jeong Han, Wang, Xiaohui, Zou, Xiaoqin, Sohma, Yoshiro, Li, Min, Hwang, Tzyh-Chang
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289160/ https://www.ncbi.nlm.nih.gov/pubmed/15767296 http://dx.doi.org/10.1085/jgp.200409228

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