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Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes

BACKGROUND: Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) plays a critical role in downregulation of antigen-activated immune response and polymorphisms at the CTLA-4 gene have been shown to be associated with several autoimmune diseases including type-1 diabetes (T1D). The etiological mutati...

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Detalles Bibliográficos
Autores principales: Purohit, Sharad, Podolsky, Robert, Collins, Christin, Zheng, Weipeng, Schatz, Desmond, Muir, Andy, Hopkins, Diane, Huang, Yi-Hua, She, Jin-Xiong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289290/
https://www.ncbi.nlm.nih.gov/pubmed/16259622
http://dx.doi.org/10.1186/1740-2557-2-8