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Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms
BACKGROUND: Human T-cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) after a long latent period. Among accessory genes encoded by HTLV-I, the tax gene is thought to play a central role in oncogenesis. However, Tax expression is disrupted by several mechanims including genetic c...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289293/ https://www.ncbi.nlm.nih.gov/pubmed/16242045 http://dx.doi.org/10.1186/1742-4690-2-64 |