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Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms

BACKGROUND: Human T-cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) after a long latent period. Among accessory genes encoded by HTLV-I, the tax gene is thought to play a central role in oncogenesis. However, Tax expression is disrupted by several mechanims including genetic c...

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Detalles Bibliográficos
Autores principales:	Taniguchi, Yuko, Nosaka, Kisato, Yasunaga, Jun-ichirou, Maeda, Michiyuki, Mueller, Nancy, Okayama, Akihiko, Matsuoka, Masao
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289293/ https://www.ncbi.nlm.nih.gov/pubmed/16242045 http://dx.doi.org/10.1186/1742-4690-2-64

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