Synergistic inhibition of human melanoma proliferation by combination treatment with B-Raf inhibitor BAY43-9006 and mTOR inhibitor Rapamycin

BACKGROUND: Targeted inhibition of protein kinases is now acknowledged as an effective approach for cancer therapy. However, targeted therapies probably have limited success because cancer cells have alternate pathways for survival and proliferation thereby avoiding inhibition. We tested the hypothe...

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Detalles Bibliográficos
Autores principales: Molhoek, Kerrington R, Brautigan, David L, Slingluff, Craig L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289294/
https://www.ncbi.nlm.nih.gov/pubmed/16255777
http://dx.doi.org/10.1186/1479-5876-3-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289294/
https://www.ncbi.nlm.nih.gov/pubmed/16255777
http://dx.doi.org/10.1186/1479-5876-3-39

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