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Allele-Specific Amplification in Cancer Revealed by SNP Array Analysis

Amplification, deletion, and loss of heterozygosity of genomic DNA are hallmarks of cancer. In recent years a variety of studies have emerged measuring total chromosomal copy number at increasingly high resolution. Similarly, loss-of-heterozygosity events have been finely mapped using high-throughpu...

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Detalles Bibliográficos
Autores principales: LaFramboise, Thomas, Weir, Barbara A, Zhao, Xiaojun, Beroukhim, Rameen, Li, Cheng, Harrington, David, Sellers, William R, Meyerson, Matthew
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1289392/
https://www.ncbi.nlm.nih.gov/pubmed/16322765
http://dx.doi.org/10.1371/journal.pcbi.0010065