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ATP-sensitive potassium channel (K(ATP )channel) expression in the normal canine pancreas and in canine insulinomas

BACKGROUND: Pancreatic beta cells express ATP-sensitive potassium (K(ATP)) channels that are needed for normal insulin secretion and are targets for drugs that modulate insulin secretion. The K(ATP )channel is composed of two subunits: a sulfonylurea receptor (SUR 1) and an inward rectifying potassi...

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Detalles Bibliográficos
Autores principales: Donley, Vicky R, Hiskett, Erin K, Kidder, Aimee C, Schermerhorn, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291378/
https://www.ncbi.nlm.nih.gov/pubmed/16266437
http://dx.doi.org/10.1186/1746-6148-1-8