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Towards a standardization of thrombin generation assessment: The influence of tissue factor, platelets and phospholipids concentration on the normal values of Thrombogram-Thrombinoscope assay

BACKGROUND: Thrombin generation assay was developed several years ago to mimic physiological coagulation mechanisms but it had important limitations. Thrombogram-Thrombinoscope assay using a fluorogenic substrate, allows obtaining thrombin generation curves in non-defibrinated platelet rich plasma (...

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Detalles Bibliográficos
Autores principales: Gerotziafas, Grigoris T, Depasse, François, Busson, Joël, Leflem, Lena, Elalamy, Ismail, Samama, Meyer M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291409/
https://www.ncbi.nlm.nih.gov/pubmed/16250908
http://dx.doi.org/10.1186/1477-9560-3-16