Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level

Promoters are molecular ‘modules’, which are controlled as individual entities yet are often analyzed by nuclease digestion methodologies which, a priori, destroy this modularity. About 40% of mammalian genes contain CpG islands in their promoters and exonic regions, which are normally unmethylated....

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Detalles Bibliográficos
Autores principales: Fatemi, Mehrnaz, Pao, Martha M., Jeong, Shinwu, Gal-Yam, Einav Nili, Egger, Gerda, Weisenberger, Daniel J., Jones, Peter A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1292996/
https://www.ncbi.nlm.nih.gov/pubmed/16314307
http://dx.doi.org/10.1093/nar/gni180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1292996/
https://www.ncbi.nlm.nih.gov/pubmed/16314307
http://dx.doi.org/10.1093/nar/gni180

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