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Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis

Extracellular fibrinolysis, controlled by the membrane-bound fibrinolytic system, is involved in cartilage damage and rheumatoid arthritis (RA) synovitis. Estrogen status and metabolism seem to be impaired in RA, and synoviocytes show receptors for estrogens. Our aims in this study were to evaluate...

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Detalles Bibliográficos
Autores principales: Guiducci, S, Del Rosso, A, Cinelli, M, Perfetto, F, Livi, R, Rossi, A, Gabrielli, A, Giacomelli, R, Iori, N, Fibbi, G, Del Rosso, M, Cerinic, M Matucci
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297569/
https://www.ncbi.nlm.nih.gov/pubmed/16277677
http://dx.doi.org/10.1186/ar1815