Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity

Osteoarthritis (OA) is a common joint disease, mainly effecting the elderly population. The cause of OA seems to be an imbalance in catabolic and anabolic factors that develops with age. IL-1 is a catabolic factor known to induce cartilage damage, and transforming growth factor (TGF)-beta is an anab...

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Detalles Bibliográficos
Autores principales: Blaney Davidson, EN, Scharstuhl, A, Vitters, EL, van der Kraan, PM, van den Berg, WB
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297583/
https://www.ncbi.nlm.nih.gov/pubmed/16277687
http://dx.doi.org/10.1186/ar1833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297583/
https://www.ncbi.nlm.nih.gov/pubmed/16277687
http://dx.doi.org/10.1186/ar1833

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