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Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity
Osteoarthritis (OA) is a common joint disease, mainly effecting the elderly population. The cause of OA seems to be an imbalance in catabolic and anabolic factors that develops with age. IL-1 is a catabolic factor known to induce cartilage damage, and transforming growth factor (TGF)-beta is an anab...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297583/ https://www.ncbi.nlm.nih.gov/pubmed/16277687 http://dx.doi.org/10.1186/ar1833 |