The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

BACKGROUND: Members of the p47 (immunity-related GTPases (IRG) family) GTPases are essential, interferon-inducible resistance factors in mice that are active against a broad spectrum of important intracellular pathogens. Surprisingly, there are no reports of p47 function in humans. RESULTS: Here we...

Descripción completa

Detalles Bibliográficos
Autores principales: Bekpen, Cemalettin, Hunn, Julia P, Rohde, Christoph, Parvanova, Iana, Guethlein, Libby, Dunn, Diane M, Glowalla, Eva, Leptin, Maria, Howard, Jonathan C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297648/
https://www.ncbi.nlm.nih.gov/pubmed/16277747
http://dx.doi.org/10.1186/gb-2005-6-11-r92

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297648/
https://www.ncbi.nlm.nih.gov/pubmed/16277747
http://dx.doi.org/10.1186/gb-2005-6-11-r92

Ejemplares similares