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Identification and characterization of high affinity antisense PNAs for the human unr (upstream of N-ras) mRNA which is uniquely overexpressed in MCF-7 breast cancer cells
We have recently shown that an MCF-7 tumor can be imaged in a mouse by PET with (64)Cu-labeled Peptide nucleic acids (PNAs) tethered to the permeation peptide Lys(4) that recognize the uniquely overexpressed and very abundant upstream of N-ras or N-ras related gene (unr mRNA) expressed in these cell...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297704/ https://www.ncbi.nlm.nih.gov/pubmed/16314303 http://dx.doi.org/10.1093/nar/gki968 |