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An obligate intermediate along the slow folding pathway of a group II intron ribozyme

Most RNA molecules collapse rapidly and reach the native state through a pathway that contains numerous traps and unproductive intermediates. The D135 group II intron ribozyme is unusual in that it can fold slowly and directly to the native state, despite its large size and structural complexity. He...

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Detalles Bibliográficos
Autores principales: Su, Linhui Julie, Waldsich, Christina, Pyle, Anna Marie
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297705/
https://www.ncbi.nlm.nih.gov/pubmed/16314300
http://dx.doi.org/10.1093/nar/gki973