A strategy using NMR peptide structures of thromboxane A2 receptor as templates to construct ligand-recognition pocket of prostacyclin receptor

BACKGROUND: Prostacyclin receptor (IP) and thromboxane A2 receptor (TP) belong to rhodopsin-type G protein-coupling receptors and respectively bind to prostacyclin and thromboxane A2 derived from arachidonic acid. Recently, we have determined the extracellular loop (eLP) structures of the human TP r...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruan, Cheng-Huai, Wu, Jaixin, Ruan, Ke-He
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298286/
https://www.ncbi.nlm.nih.gov/pubmed/16271145
http://dx.doi.org/10.1186/1471-2091-6-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298286/
https://www.ncbi.nlm.nih.gov/pubmed/16271145
http://dx.doi.org/10.1186/1471-2091-6-23

Ejemplares similares