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Specific distribution of overexpressed aurora B kinase in interphase normal epithelial cells

BACKGROUND: It is known that aurora B, a chromosomal passenger protein responsible for the proper progression of mitosis and cytokinesis, is overexpressed throughout the cell cycle in cancer cells. Overexpression of aurora B produced multinuclearity and induced aggressive metastasis, suggesting that...

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Detalles Bibliográficos
Autores principales: Abdullah, Ash-shafie, Foong, Charlene, Murata-Hori, Maki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298314/
https://www.ncbi.nlm.nih.gov/pubmed/16281968
http://dx.doi.org/10.1186/1475-2867-5-31