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The natural history of EGFR and EGFRvIII in glioblastoma patients

BACKGROUND: The epidermal growth factor receptor (EGFR) is over expressed in approximately 50–60% of glioblastoma (GBM) tumors, and the most common EGFR mutant, EGFRvIII, is expressed in 24–67% of cases. This study was designed to address whether over expressed EGFR or EGFRvIII is an actual independ...

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Detalles Bibliográficos
Autores principales: Heimberger, Amy B, Suki, Dima, Yang, David, Shi, Weiming, Aldape, Kenneth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298339/
https://www.ncbi.nlm.nih.gov/pubmed/16236164
http://dx.doi.org/10.1186/1479-5876-3-38