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A Network of Multi-Tasking Proteins at the DNA Replication Fork Preserves Genome Stability
To elucidate the network that maintains high fidelity genome replication, we have introduced two conditional mutant alleles of DNA2, an essential DNA replication gene, into each of the approximately 4,700 viable yeast deletion mutants and determined the fitness of the double mutants. Fifty-six DNA2-...
Autores principales: | Budd, Martin E, Tong, Amy Hin Yan, Polaczek, Piotr, Peng, Xiao, Boone, Charles, Campbell, Judith L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298934/ https://www.ncbi.nlm.nih.gov/pubmed/16327883 http://dx.doi.org/10.1371/journal.pgen.0010061 |
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