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A Novel Endogenous Inhibitor of the Secreted Streptococcal NAD-Glycohydrolase

The Streptococcus pyogenes NAD-glycohydrolase (SPN) is a toxic enzyme that is introduced into infected host cells by the cytolysin-mediated translocation pathway. However, how S. pyogenes protects itself from the self-toxicity of SPN had been unknown. In this report, we describe immunity factor for...

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Detalles Bibliográficos
Autores principales: Meehl, Michael A, Pinkner, Jerome S, Anderson, Patricia J, Hultgren, Scott J, Caparon, Michael G
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298937/
https://www.ncbi.nlm.nih.gov/pubmed/16333395
http://dx.doi.org/10.1371/journal.ppat.0010035