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A Novel Endogenous Inhibitor of the Secreted Streptococcal NAD-Glycohydrolase
The Streptococcus pyogenes NAD-glycohydrolase (SPN) is a toxic enzyme that is introduced into infected host cells by the cytolysin-mediated translocation pathway. However, how S. pyogenes protects itself from the self-toxicity of SPN had been unknown. In this report, we describe immunity factor for...
Autores principales: | Meehl, Michael A, Pinkner, Jerome S, Anderson, Patricia J, Hultgren, Scott J, Caparon, Michael G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298937/ https://www.ncbi.nlm.nih.gov/pubmed/16333395 http://dx.doi.org/10.1371/journal.ppat.0010035 |
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