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Functional and Genetic Analysis of Coronavirus Replicase-Transcriptase Proteins

The coronavirus replicase-transcriptase complex is an assembly of viral and cellular proteins that mediate the synthesis of genome and subgenome-sized mRNAs in the virus-infected cell. Here, we report a genetic and functional analysis of 19 temperature-sensitive (ts) mutants of Murine hepatitis viru...

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Detalles Bibliográficos
Autores principales: Sawicki, Stanley G, Sawicki, Dorothea L, Younker, Diane, Meyer, Yvonne, Thiel, Volker, Stokes, Helen, Siddell, Stuart G
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298938/
https://www.ncbi.nlm.nih.gov/pubmed/16341254
http://dx.doi.org/10.1371/journal.ppat.0010039