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Citrullination: a small change for a protein with great consequences for rheumatoid arthritis
A new autoantibody activity, which is almost 100% specific for rheumatoid arthritis (RA), has been found. The essential part of the B-cell epitope is a modified form of arginine (ie citrulline). The conversion of protein-contained arginine to citrulline is an enzymatic process that is carried out by...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2000
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130012/ https://www.ncbi.nlm.nih.gov/pubmed/11094435 http://dx.doi.org/10.1186/ar95 |