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Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation
In Trypanosoma brucei, DNA recombination is crucial in antigenic variation, a strategy for evading the mammalian host immune system found in a wide variety of pathogens. T.brucei has the capacity to encode >1000 antigenically distinct variant surface glycoproteins (VSGs). By ensuring that only on...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1301600/ https://www.ncbi.nlm.nih.gov/pubmed/16326865 http://dx.doi.org/10.1093/nar/gki996 |