Cargando…
Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation
In Trypanosoma brucei, DNA recombination is crucial in antigenic variation, a strategy for evading the mammalian host immune system found in a wide variety of pathogens. T.brucei has the capacity to encode >1000 antigenically distinct variant surface glycoproteins (VSGs). By ensuring that only on...
Autores principales: | Proudfoot, Chris, McCulloch, Richard |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1301600/ https://www.ncbi.nlm.nih.gov/pubmed/16326865 http://dx.doi.org/10.1093/nar/gki996 |
Ejemplares similares
-
Interactions among Trypanosoma brucei RAD51 paralogues in DNA repair and antigenic variation
por: Dobson, Rachel, et al.
Publicado: (2011) -
Antigenic Variation in Trypanosoma brucei: Joining the DOTs
por: Stockdale, Chris, et al.
Publicado: (2008) -
RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in Trypanosoma brucei
por: Girasol, Mark John, et al.
Publicado: (2023) -
Trypanosoma brucei BRCA2 acts in a life cycle-specific genome stability process and dictates BRC repeat number-dependent RAD51 subnuclear dynamics
por: Trenaman, Anna, et al.
Publicado: (2013) -
Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation
por: Devlin, Rebecca, et al.
Publicado: (2016)