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Analysis of vertebrate genomes suggests a new model for clade B serpin evolution

BACKGROUND: The human genome contains 13 clade B serpin genes at two loci, 6p25 and 18q21. The three genes at 6p25 all conform to a 7-exon gene structure with conserved intron positioning and phasing, however, at 18q21 there are two 7-exon genes and eight genes with an additional exon yielding an 8-...

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Detalles Bibliográficos
Autores principales: Kaiserman, Dion, Bird, Phillip I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1308813/
https://www.ncbi.nlm.nih.gov/pubmed/16305753
http://dx.doi.org/10.1186/1471-2164-6-167