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Nurr1 dependent regulation of pro-inflammatory mediators in immortalised synovial fibroblasts

BACKGROUND: Nurr1 is an orphan member of the nuclear receptor superfamily; these orphan receptors are a group for which a ligand has yet to be identified. Nurr1 has been shown to regulate the expression of a small number of genes as a monomeric, constitutively active receptor. These Nurr1 regulated...

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Detalles Bibliográficos
Autores principales: Davies, Mark R, Harding, Christine J, Raines, Stephanie, Tolley, Kurt, Parker, Andrew E, Downey-Jones, Mark, Needham, Maurice RC
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1308852/
https://www.ncbi.nlm.nih.gov/pubmed/16309552
http://dx.doi.org/10.1186/1476-9255-2-15