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ASIC3, an acid-sensing ion channel, is expressed in metaboreceptive sensory neurons

BACKGROUND: ASIC3, the most sensitive of the acid-sensing ion channels, depolarizes certain rat sensory neurons when lactic acid appears in the extracellular medium. Two functions have been proposed for it: 1) ASIC3 might trigger ischemic pain in heart and muscle; 2) it might contribute to some form...

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Detalles Bibliográficos
Autores principales: Molliver, Derek C, Immke, David C, Fierro, Leonardo, Paré, Michel, Rice, Frank L, McCleskey, Edwin W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1308857/
https://www.ncbi.nlm.nih.gov/pubmed/16305749
http://dx.doi.org/10.1186/1744-8069-1-35