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Revealing Posttranscriptional Regulatory Elements Through Network-Level Conservation

We used network-level conservation between pairs of fly (Drosophila melanogaster/D. pseudoobscura) and worm (Caenorhabditis elegans/C. briggsae) genomes to detect highly conserved mRNA motifs in 3′ untranslated regions. Many of these elements are complementary to the 5′ extremity of known microRNAs...

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Detalles Bibliográficos
Autores principales: Chan, Chang S, Elemento, Olivier, Tavazoie, Saeed
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1309705/
https://www.ncbi.nlm.nih.gov/pubmed/16355253
http://dx.doi.org/10.1371/journal.pcbi.0010069