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Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases

BACKGROUND: The family of proprotein convertases has been recently implicated in tumorigenesis and metastasis in animal models. However, these studies have not yet been completely corroborated in human tumors. METHODS: Using RT PCR, immunoblot and immunohistochemistry we assessed the presence and th...

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Detalles Bibliográficos
Autores principales: Tzimas, George N, Chevet, Eric, Jenna, Sarah, Nguyên, Duc Thang, Khatib, Abdel M, Marcus, Victoria, Zhang, Yi, Chrétien, Michel, Seidah, Nabil, Metrakos, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310616/
https://www.ncbi.nlm.nih.gov/pubmed/16293189
http://dx.doi.org/10.1186/1471-2407-5-149