Cargando…

Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases

BACKGROUND: The family of proprotein convertases has been recently implicated in tumorigenesis and metastasis in animal models. However, these studies have not yet been completely corroborated in human tumors. METHODS: Using RT PCR, immunoblot and immunohistochemistry we assessed the presence and th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tzimas, George N, Chevet, Eric, Jenna, Sarah, Nguyên, Duc Thang, Khatib, Abdel M, Marcus, Victoria, Zhang, Yi, Chrétien, Michel, Seidah, Nabil, Metrakos, Peter
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310616/ https://www.ncbi.nlm.nih.gov/pubmed/16293189 http://dx.doi.org/10.1186/1471-2407-5-149

Ejemplares similares

Discovery of the Proprotein Convertases and their Inhibitors
por: Khatib, Abdel-Majid, et al.
Publicado: (2006)

Is there a link between proprotein convertase PC7 activity and human lipid homeostasis?
por: Guillemot, Johann, et al.
Publicado: (2014)

The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model
por: Sun, Xiaowei, et al.
Publicado: (2009)

Comparative analysis of expression of the proprotein convertases furin, PACE4, PC1 and PC2 in human lung tumours.
por: Mbikay, M., et al.
Publicado: (1997)

The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments
Publicado: (1996)

Hysteretic Behavior of Proprotein Convertase 1/3 (PC1/3)
por: Icimoto, Marcelo Y., et al.
Publicado: (2011)

Implication of proprotein convertases in the processing and spread of severe acute respiratory syndrome coronavirus
por: Bergeron, Eric, et al.
Publicado: (2005)

The proprotein convertase PC1/3 regulates TLR9 trafficking and the associated signaling pathways
por: Duhamel, M., et al.
Publicado: (2016)

Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth
por: Declercq, Jeroen, et al.
Publicado: (2015)

How Do Enveloped Viruses Exploit the Secretory Proprotein Convertases to Regulate Infectivity and Spread?
por: Seidah, Nabil G., et al.
Publicado: (2021)

In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23
por: Al Rifai, Omar, et al.
Publicado: (2021)

Furin Is the Major Proprotein Convertase Required for KISS1-to-Kisspeptin Processing
por: Harihar, Sitaram, et al.
Publicado: (2014)

Proprotein convertases: Key players in inflammation-related malignancies and metastasis
por: Siegfried, Geraldine, et al.
Publicado: (2020)

Repression of liver colorectal metastasis by the serpin Spn4A a naturally occurring inhibitor of the constitutive secretory proprotein convertases
por: Sfaxi, Fatma, et al.
Publicado: (2014)

Proprotein Convertases and the Complement System
por: Dobó, József, et al.
Publicado: (2022)

Proprotein Convertase 1/3 (PC1/3) in the Rat Alveolar Macrophage Cell Line NR8383: Localization, Trafficking and Effects on Cytokine Secretion
por: Gagnon, Hugo, et al.
Publicado: (2013)

Phylogenetic analysis of Amphioxus genes of the proprotein convertase family, including aPC6C, a marker of epithelial fusions during embryology
por: Bertrand, Stéphanie, et al.
Publicado: (2006)

Proprotein convertase subtilisin/kexin Type 9 is required for Ahnak-mediated metastasis of melanoma into lung epithelial cells
por: Suh, Jung Min, et al.
Publicado: (2021)

Shedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression
por: Duval, Stéphanie, et al.
Publicado: (2020)

The proprotein convertase SKI-1/S1P is a critical host factor for Nairobi sheep disease virus infectivity
por: Bost, Caroline, et al.
Publicado: (2023)

The proprotein convertase furin is required for trophoblast syncytialization
por: Zhou, Z, et al.
Publicado: (2013)

Proprotein convertases in high-density lipoprotein metabolism
por: Choi, Seungbum, et al.
Publicado: (2013)

Characterization of Proprotein Convertases and Their Involvement in Virus Propagation
por: Garten, Wolfgang
Publicado: (2018)

Testicular Germ Cell Tumours and Proprotein Convertases
por: Velado-Eguskiza, Aitziber, et al.
Publicado: (2022)

The Role of Proprotein Convertases in Upper Airway Remodeling
por: Lee, Sang-Nam, et al.
Publicado: (2022)

Roles of the low density lipoprotein receptor and related receptors in inhibition of lipoprotein(a) internalization by proprotein convertase subtilisin/kexin type 9
por: Romagnuolo, Rocco, et al.
Publicado: (2017)

Cleavage of a Neuroinvasive Human Respiratory Virus Spike Glycoprotein by Proprotein Convertases Modulates Neurovirulence and Virus Spread within the Central Nervous System
por: Le Coupanec, Alain, et al.
Publicado: (2015)

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Can Mediate Degradation of the Low Density Lipoprotein Receptor-Related Protein 1 (LRP-1)
por: Canuel, Maryssa, et al.
Publicado: (2013)

Proprotein Convertases Process Pmel17 during Secretion
por: Leonhardt, Ralf M., et al.
Publicado: (2011)

OFF-State-Specific Inhibition of the Proprotein Convertase Furin
por: Dahms, Sven O., et al.
Publicado: (2021)

What Are the Roles of Proprotein Convertases in the Immune Escape of Tumors?
por: Mehranzadeh, Elham, et al.
Publicado: (2022)

The Role of Proprotein Convertases in the Regulation of the Function of Immune Cells in the Oncoimmune Response
por: Rose, Mélanie, et al.
Publicado: (2021)

Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst
por: Mesnard, Daniel, et al.
Publicado: (2010)

Genetics of the First Seven Proprotein Convertase Enzymes in Health and Disease
por: Turpeinen, Hannu, et al.
Publicado: (2013)

Relative expression of proprotein convertases in rat ovaries during pregnancy
por: Kwok, Simon CM, et al.
Publicado: (2013)

Small Molecule Proprotein Convertase Inhibitors for Inhibition of Embryo Implantation
por: Ho, Huiting, et al.
Publicado: (2013)

Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality
por: Fernandez, C., et al.
Publicado: (2018)

Myeloid cell expressed proprotein convertase FURIN attenuates inflammation
por: Cordova, Zuzet Martinez, et al.
Publicado: (2016)

Proprotein Convertase Subtilisin/Kexin 6 in Cardiovascular Biology and Disease
por: Wu, Qingyu, et al.
Publicado: (2022)

Proprotein convertase furin inhibits matrix metalloproteinase 13 in a TGFβ-dependent manner and limits osteoarthritis in mice
por: Lin, Hilène, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_jhthi7ob68qobj2u3m7487kbtv