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The leucine rich region of DNA-PKcs contributes to its innate DNA affinity
DNA-PK is a protein complex that consists of a DNA-binding, regulatory subunit [Ku] and a larger ∼465 kDa catalytic subunit [DNA-PKcs], a serine/threonine protein kinase. The kinase activity of DNA-PKcs resides between residues 3745 and 4013, a PI3 kinase domain. Another recognized domain within thi...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310895/ https://www.ncbi.nlm.nih.gov/pubmed/16340007 http://dx.doi.org/10.1093/nar/gki990 |