Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI–DNA complexes

DNA base flipping is an important mechanism in molecular enzymology, but its study is limited by the lack of an accessible and reliable diagnostic technique. A series of crystalline complexes of a DNA methyltransferase, M.HhaI, and its cognate DNA, in which a fluorescent nucleobase analogue, 2-amino...

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Detalles Bibliográficos
Autores principales: Neely, Robert K., Daujotyte, Dalia, Grazulis, Saulius, Magennis, Steven W., Dryden, David T. F., Klimašauskas, Saulius, Jones, Anita C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310896/
https://www.ncbi.nlm.nih.gov/pubmed/16340006
http://dx.doi.org/10.1093/nar/gki995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310896/
https://www.ncbi.nlm.nih.gov/pubmed/16340006
http://dx.doi.org/10.1093/nar/gki995

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