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Improved alignment of nucleosome DNA sequences using a mixture model

DNA sequences that are present in nucleosomes have a preferential ∼10 bp periodicity of certain dinucleotide signals (1,2), but the overall sequence similarity of the nucleosomal DNA is weak, and traditional multiple sequence alignment tools fail to yield meaningful alignments. We develop a mixture...

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Detalles Bibliográficos
Autores principales: Wang, Ji-Ping Z., Widom, Jonathan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310902/
https://www.ncbi.nlm.nih.gov/pubmed/16339114
http://dx.doi.org/10.1093/nar/gki977