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Improved alignment of nucleosome DNA sequences using a mixture model
DNA sequences that are present in nucleosomes have a preferential ∼10 bp periodicity of certain dinucleotide signals (1,2), but the overall sequence similarity of the nucleosomal DNA is weak, and traditional multiple sequence alignment tools fail to yield meaningful alignments. We develop a mixture...
Autores principales: | Wang, Ji-Ping Z., Widom, Jonathan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310902/ https://www.ncbi.nlm.nih.gov/pubmed/16339114 http://dx.doi.org/10.1093/nar/gki977 |
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