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A conserved and species-specific functional interaction between the Werner syndrome-like exonuclease atWEX and the Ku heterodimer in Arabidopsis

Werner syndrome is associated with mutations in the DNA helicase RecQ3 [a.k.a. Homo sapiens (hs)WRN]. The function of hsWRN is unknown although biochemical studies suggest a role in DNA ends stability and repair. Unlike other RecQ family members, hsWRN possesses an N-terminal domain with exonuclease...

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Detalles Bibliográficos
Autores principales: Li, Baomin, Conway, Nathan, Navarro, Sonia, Comai, Luca, Comai, Lucio
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310904/
https://www.ncbi.nlm.nih.gov/pubmed/16396834
http://dx.doi.org/10.1093/nar/gki984