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SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly

We have isolated the human protein SNEV as downregulated in replicatively senescent cells. Sequence homology to the yeast splicing factor Prp19 suggested that SNEV might be the orthologue of Prp19 and therefore might also be involved in pre-mRNA splicing. We have used various approaches including ge...

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Detalles Bibliográficos
Autores principales: Grillari, Johannes, Ajuh, Paul, Stadler, Guido, Löscher, Marlies, Voglauer, Regina, Ernst, Wolfgang, Chusainow, Janet, Eisenhaber, Frank, Pokar, Marion, Fortschegger, Klaus, Grey, Martin, Lamond, Angus I., Katinger, Hermann
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310963/
https://www.ncbi.nlm.nih.gov/pubmed/16332694
http://dx.doi.org/10.1093/nar/gki986