Cargando…

SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly

We have isolated the human protein SNEV as downregulated in replicatively senescent cells. Sequence homology to the yeast splicing factor Prp19 suggested that SNEV might be the orthologue of Prp19 and therefore might also be involved in pre-mRNA splicing. We have used various approaches including ge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grillari, Johannes, Ajuh, Paul, Stadler, Guido, Löscher, Marlies, Voglauer, Regina, Ernst, Wolfgang, Chusainow, Janet, Eisenhaber, Frank, Pokar, Marion, Fortschegger, Klaus, Grey, Martin, Lamond, Angus I., Katinger, Hermann
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310963/ https://www.ncbi.nlm.nih.gov/pubmed/16332694 http://dx.doi.org/10.1093/nar/gki986

Ejemplares similares

Blom7α Is a Novel Heterogeneous Nuclear Ribonucleoprotein K Homology Domain Protein Involved in Pre-mRNA Splicing That Interacts with SNEV(Prp19-Pso4)
por: Grillari, Johannes, et al.
Publicado: (2009)

Inhibition of Pre-mRNA Splicing by a Synthetic Blom7α-Interacting Small RNA
por: Löscher, Marlies, et al.
Publicado: (2012)

SNEV(P) (rp19/) (PSO) (4) deficiency increases PUVA‐induced senescence in mouse skin
por: Monteforte, Rossella, et al.
Publicado: (2016)

SNEV(hPrp19/hPso4) Regulates Adipogenesis of Human Adipose Stromal Cells
por: Khan, Abdulhameed, et al.
Publicado: (2016)

ATM-dependent phosphorylation of SNEV(hPrp19/hPso4) is involved in extending cellular life span and suppression of apoptosis
por: Dellago, Hanna, et al.
Publicado: (2012)

Contributions of DNA interstrand cross-links to aging of cells and organisms
por: Grillari, Johannes, et al.
Publicado: (2007)

Identification of evolutionarily conserved genetic regulators of cellular aging
por: Laschober, Gerhard T, et al.
Publicado: (2010)

miR-17–92 cluster: ups and downs in cancer and aging
por: Grillari, Johannes, et al.
Publicado: (2010)

Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development
por: Gómez-Redondo, Isabel, et al.
Publicado: (2022)

Evolutionarily divergent spliceosomal snRNAs and a conserved non-coding RNA processing motif in Giardia lamblia
por: Hudson, Andrew J., et al.
Publicado: (2012)

Ebola virus inclusion bodies are liquid organelles whose formation is facilitated by nucleoprotein oligomerization
por: Bodmer, Bianca S., et al.
Publicado: (2023)

Whose voice? Whose choice? Whose power?
por: Chamberlin, Judi
Publicado: (2007)

Secretion of microvesicular miRNAs in cellular and organismal aging
por: Weilner, Sylvia, et al.
Publicado: (2013)

The role of microRNAs in cellular senescence and age-related conditions of cartilage and bone: A review
por: Weilner, Sylvia, et al.
Publicado: (2015)

Oligomerization of ZFYVE27 (Protrudin) Is Necessary to Promote Neurite Extension
por: Pantakani, D. V. Krishna, et al.
Publicado: (2011)

Oligomerization and endocytosis of Hedgehog is necessary for its efficient exovesicular secretion
por: Parchure, Anup, et al.
Publicado: (2015)

TDP-43 Oligomerization and Phase Separation Properties Are Necessary for Autoregulation
por: Koehler, Lydia C., et al.
Publicado: (2022)

Whose Copy? Whose Rights?
por: Gass, Andy, et al.
Publicado: (2004)

High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan
por: Dellago, Hanna, et al.
Publicado: (2013)

Secreted microvesicular miR‐31 inhibits osteogenic differentiation of mesenchymal stem cells
por: Weilner, Sylvia, et al.
Publicado: (2016)

Spliceosome Database: a tool for tracking components of the spliceosome
por: Cvitkovic, Ivan, et al.
Publicado: (2013)

Function of a membrane-embedded domain evolutionarily multiplied in the GPI lipid anchor pathway proteins PIG-B, PIG-M, PIG-U, PIG-W, PIG-V, and PIG-Z
por: Eisenhaber, Birgit, et al.
Publicado: (2018)

Structures of the human pre-catalytic spliceosome and its precursor spliceosome
por: Zhan, Xiechao, et al.
Publicado: (2018)

Human spliceosomal snRNA sequence variants generate variant spliceosomes
por: Mabin, Justin W., et al.
Publicado: (2021)

Spliceosome assembly and regulation: insights from analysis of highly reduced spliceosomes
por: Black, Corbin S., et al.
Publicado: (2023)

Challenging the spliceosome machine
por: Weir, Michael, et al.
Publicado: (2006)

Structure of spliceosomal ribonucleoproteins
por: Krummel, Daniel Aaron Pomeranz, et al.
Publicado: (2010)

CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast
por: Nguyen, Thi Hoang Duong, et al.
Publicado: (2016)

Whose Sperm?
por: Amann, R. P.
Publicado: (1994)

Who's whose?
por: Gooden, Philip
Publicado: (2009)

Whose Dog Is It?
Publicado: (1877)

Comment — WHO outsourcing dilemma: for whose benefit, at whose expense?
por: Sharma, Jeevan Raj, et al.
Publicado: (2017)

Patterns of conservation of spliceosomal intron structures and spliceosome divergence in representatives of the diplomonad and parabasalid lineages
por: Hudson, Andrew J., et al.
Publicado: (2019)

The spliceosome as target for anticancer treatment
por: van Alphen, R J, et al.
Publicado: (2009)

Origin and evolution of spliceosomal introns
por: Rogozin, Igor B, et al.
Publicado: (2012)

Spliceosome Mutations in Uveal Melanoma
por: Nguyen, Josephine Q.N., et al.
Publicado: (2020)

Spliceosomal snRNA Epitranscriptomics
por: Morais, Pedro, et al.
Publicado: (2021)

The impact of spliceosome mutations in MDS
por: Boultwood, Jacqueline, et al.
Publicado: (2019)

Prevalent and distinct spliceosomal 3′-end processing mechanisms for fungal telomerase RNA
por: Qi, Xiaodong, et al.
Publicado: (2015)

Sicily: whose victory?
por: Blumenson, Martin
Publicado: (1969)

Cannot write session to /tmp/vufind_sessions/sess_bktrkihj1obc4v08siggo91cu8