The naturally trans-acting ribozyme RNase P RNA has leadzyme properties

Divalent metal ions promote hydrolysis of RNA backbones generating 5′OH and 2′;3′P as cleavage products. In these reactions, the neighboring 2′OH act as the nucleophile. RNA catalyzed reactions also require divalent metal ions and a number of different metal ions function in RNA mediated cleavage of...

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Detalles Bibliográficos
Autores principales: Kikovska, Ema, Mikkelsen, Nils-Egil, Kirsebom, Leif A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310964/
https://www.ncbi.nlm.nih.gov/pubmed/16332695
http://dx.doi.org/10.1093/nar/gki993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310964/
https://www.ncbi.nlm.nih.gov/pubmed/16332695
http://dx.doi.org/10.1093/nar/gki993

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