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Ablation of the Sam68 RNA Binding Protein Protects Mice from Age-Related Bone Loss
The Src substrate associated in mitosis of 68 kDa (Sam68) is a KH-type RNA binding protein that has been shown to regulate several aspects of RNA metabolism; however, its physiologic role has remained elusive. Herein we report the generation of Sam68-null mice by homologous recombination. Aged Sam68...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315279/ https://www.ncbi.nlm.nih.gov/pubmed/16362077 http://dx.doi.org/10.1371/journal.pgen.0010074 |