Ablation of the Sam68 RNA Binding Protein Protects Mice from Age-Related Bone Loss

The Src substrate associated in mitosis of 68 kDa (Sam68) is a KH-type RNA binding protein that has been shown to regulate several aspects of RNA metabolism; however, its physiologic role has remained elusive. Herein we report the generation of Sam68-null mice by homologous recombination. Aged Sam68...

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Detalles Bibliográficos
Autores principales: Richard, Stéphane, Torabi, Nazi, Franco, Gladys Valverde, Tremblay, Guy A, Chen, Taiping, Vogel, Gillian, Morel, Mélanie, Cléroux, Patrick, Forget-Richard, Alexandre, Komarova, Svetlana, Tremblay, Michel L, Li, Wei, Li, Ailian, Gao, Yun Jing, Henderson, Janet E
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315279/
https://www.ncbi.nlm.nih.gov/pubmed/16362077
http://dx.doi.org/10.1371/journal.pgen.0010074

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