The Flavoring Agent Dihydrocoumarin Reverses Epigenetic Silencing and Inhibits Sirtuin Deacetylases

Sirtuins are a family of phylogenetically conserved nicotinamide adenine dinucleotide-dependent deacetylases that have a firmly established role in aging. Using a simple Saccharomyces cerevisiae yeast heterochromatic derepression assay, we tested a number of environmental chemicals to address the po...

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Detalles Bibliográficos
Autores principales: Olaharski, Andrew J, Rine, Jasper, Marshall, Brett L, Babiarz, Joshua, Zhang, Luoping, Verdin, Eric, Smith, Martyn T
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315280/
https://www.ncbi.nlm.nih.gov/pubmed/16362078
http://dx.doi.org/10.1371/journal.pgen.0010077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315280/
https://www.ncbi.nlm.nih.gov/pubmed/16362078
http://dx.doi.org/10.1371/journal.pgen.0010077

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