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Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory response

BACKGROUND: Bacterial and viral exacerbations play a crucial role in a variety of lung diseases including COPD or asthma. Since the lung epithelium is a major source of various inflammatory mediators that affect the immune response, we analyzed the inflammatory reaction of primary lung epithelial ce...

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Detalles Bibliográficos
Autores principales: Ritter, Mirko, Mennerich, Detlev, Weith, Andreas, Seither, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1315317/
https://www.ncbi.nlm.nih.gov/pubmed/16316467
http://dx.doi.org/10.1186/1476-9255-2-16