Developing a programmed restriction endonuclease for highly specific DNA cleavage

Specific cleavage of large DNA molecules at few sites, necessary for the analysis of genomic DNA or for targeting individual genes in complex genomes, requires endonucleases of extremely high specificity. Restriction endonucleases (REase) that recognize DNA sequences of 4–8 bp are not sufficiently s...

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Detalles Bibliográficos
Autores principales: Eisenschmidt, Kristin, Lanio, Thomas, Simoncsits, András, Jeltsch, Albert, Pingoud, Vera, Wende, Wolfgang, Pingoud, Alfred
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316111/
https://www.ncbi.nlm.nih.gov/pubmed/16356926
http://dx.doi.org/10.1093/nar/gki1009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316111/
https://www.ncbi.nlm.nih.gov/pubmed/16356926
http://dx.doi.org/10.1093/nar/gki1009

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