Cargando…
Distortion of quantitative genomic and expression hybridization by C(o)t-1 DNA: mitigation of this effect
Cross-hybridization of repetitive sequences in genomic and expression arrays is reported to be suppressed with repeat-blocking nucleic acids (C(o)t-1 DNA). Contrary to expectation, we demonstrated that C(o)t-1 also enhanced non-specific hybridization between probes and genomic targets. When added to...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316118/ https://www.ncbi.nlm.nih.gov/pubmed/16356923 http://dx.doi.org/10.1093/nar/gni190 |